Nanopore sensing reveals a preferential pathway for the co-translocational unfolding of a conjugative relaxase–DNA complex

Bacterial conjugation is the main mechanism for the dissemination of antibiotic resistance genes. A single DNA strand of the conjugative plasmid is transferred across bacterial membranes covalently bound to a large multi-domain protein, named relaxase, which must be unfolded to traverse the secretio...

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Detalles Bibliográficos
Autores principales: Valenzuela-Gómez, Fernando, Arechaga, Ignacio, Cabezón, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359608/
https://www.ncbi.nlm.nih.gov/pubmed/37264907
http://dx.doi.org/10.1093/nar/gkad492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359608/
https://www.ncbi.nlm.nih.gov/pubmed/37264907
http://dx.doi.org/10.1093/nar/gkad492

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