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Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin

Sperm chromatin retains small amounts of histones, and chromatin states of sperm mirror gene expression programs of the next generation. However, it remains largely unknown how paternal epigenetic information is transmitted through sperm chromatin. Here, we present a novel mouse model of paternal ep...

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Detalles Bibliográficos
Autores principales: Sakashita, Akihiko, Ooga, Masatoshi, Otsuka, Kai, Maezawa, So, Takeuchi, Chikara, Wakayama, Sayaka, Wakayama, Teruhiko, Namekawa, Satoshi H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359620/
https://www.ncbi.nlm.nih.gov/pubmed/37283086
http://dx.doi.org/10.1093/nar/gkad479