Sordarin bound eEF2 unlocks spontaneous forward and reverse translocation on CrPV IRES

The Intergenic Region Internal Ribosome Entry Sites (IGR IRESs) of Discistroviridae promote protein synthesis without initiation factors, with IRES translocation by elongation factor 2 (eEF2) being the first factor-catalysed reaction. Here, we developed a system that allows for the observation of in...

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Detalles Bibliográficos
Autores principales: Ou, Zheren, Petrov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359634/
https://www.ncbi.nlm.nih.gov/pubmed/37283061
http://dx.doi.org/10.1093/nar/gkad476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359634/
https://www.ncbi.nlm.nih.gov/pubmed/37283061
http://dx.doi.org/10.1093/nar/gkad476

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