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Sordarin bound eEF2 unlocks spontaneous forward and reverse translocation on CrPV IRES
The Intergenic Region Internal Ribosome Entry Sites (IGR IRESs) of Discistroviridae promote protein synthesis without initiation factors, with IRES translocation by elongation factor 2 (eEF2) being the first factor-catalysed reaction. Here, we developed a system that allows for the observation of in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359634/ https://www.ncbi.nlm.nih.gov/pubmed/37283061 http://dx.doi.org/10.1093/nar/gkad476 |