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The broad-spectrum activity of perampanel: state of the art and future perspective of AMPA antagonism beyond epilepsy

Glutamate is the brain’s main excitatory neurotransmitter. Glutamatergic neurons primarily compose basic neuronal networks, especially in the cortex. An imbalance of excitatory and inhibitory activities may result in epilepsy or other neurological and psychiatric conditions. Among glutamate receptor...

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Detalles Bibliográficos
Autores principales: Perversi, Fabio, Costa, Cinzia, Labate, Angelo, Lattanzi, Simona, Liguori, Claudio, Maschio, Marta, Meletti, Stefano, Nobili, Lino, Operto, Francesca Felicia, Romigi, Andrea, Russo, Emilio, Di Bonaventura, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359664/
https://www.ncbi.nlm.nih.gov/pubmed/37483446
http://dx.doi.org/10.3389/fneur.2023.1182304