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The broad-spectrum activity of perampanel: state of the art and future perspective of AMPA antagonism beyond epilepsy
Glutamate is the brain’s main excitatory neurotransmitter. Glutamatergic neurons primarily compose basic neuronal networks, especially in the cortex. An imbalance of excitatory and inhibitory activities may result in epilepsy or other neurological and psychiatric conditions. Among glutamate receptor...
Autores principales: | Perversi, Fabio, Costa, Cinzia, Labate, Angelo, Lattanzi, Simona, Liguori, Claudio, Maschio, Marta, Meletti, Stefano, Nobili, Lino, Operto, Francesca Felicia, Romigi, Andrea, Russo, Emilio, Di Bonaventura, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359664/ https://www.ncbi.nlm.nih.gov/pubmed/37483446 http://dx.doi.org/10.3389/fneur.2023.1182304 |
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