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Blood Concentration of Cabazitaxel in a Patient Whose General Condition Worsened with Concomitant Use of Clarithromycin

We encountered a case in which the general condition of a patient receiving cabazitaxel worsened with concomitant use of clarithromycin. Cabazitaxel is metabolized mainly by CYP3A4, and the frequency of adverse events is known to increase with increasing exposure. Although these drugs are not often...

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Detalles Bibliográficos
Autores principales: Katsumi, Shigeaki, Araki, Takuya, Yashima, Hideaki, Miyazawa, Yoshiyuki, Suzuki, Kazuhiro, Yamamoto, Koujirou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359678/
https://www.ncbi.nlm.nih.gov/pubmed/37485011
http://dx.doi.org/10.1159/000530547