Preclinical evaluations of Pfs25-EPA and Pfs230D1-EPA in AS01 for a vaccine to reduce malaria transmission

Malaria transmission-blocking vaccine candidates Pfs25-EPA and Pfs230D1-EPA target sexual stage development of Plasmodium falciparum parasites in the mosquito host, thereby reducing mosquito infectivity. When formulated on Alhydrogel, Pfs25-EPA has demonstrated safety and immunogenicity in a phase 1...

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Detalles Bibliográficos
Autores principales: Rausch, Kelly M., Barnafo, Emma K., Lambert, Lynn E., Muratova, Olga, Gorres, J. Patrick, Anderson, Charles, Narum, David L., Wu, Yimin, Morrison, Robert D., Zaidi, Irfan, Duffy, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359932/
https://www.ncbi.nlm.nih.gov/pubmed/37485364
http://dx.doi.org/10.1016/j.isci.2023.107192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359932/
https://www.ncbi.nlm.nih.gov/pubmed/37485364
http://dx.doi.org/10.1016/j.isci.2023.107192

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