External control arms: COVID-19 reveals the merits of using real world evidence in real-time for clinical and public health investigations

Randomized controlled trials are considered the ‘gold standard’ to reduce bias by randomizing patients to an experimental intervention, versus placebo or standard of care cohort. There are inherent challenges to enrolling a standard of care or cohorts: costs, site engagement logistics, socioeconomic...

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Detalles Bibliográficos
Autores principales: Silva, Patrick, Janjan, Nora, Ramos, Kenneth S., Udeani, George, Zhong, Lixian, Ory, Marcia G., Smith, Matthew Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359981/
https://www.ncbi.nlm.nih.gov/pubmed/37484840
http://dx.doi.org/10.3389/fmed.2023.1198088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359981/
https://www.ncbi.nlm.nih.gov/pubmed/37484840
http://dx.doi.org/10.3389/fmed.2023.1198088

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