Prevention of noise-induced hearing loss by calpain inhibitor MDL-28170 is associated with upregulation of PI3K/Akt survival signaling pathway

INTRODUCTION: Noise-induced calcium overload in sensory hair cells has been well documented as an early step in the pathogenesis of noise-induced hearing loss (NIHL). Alterations in cellular calcium homeostasis mediate a series of cellular events, including activation of calcium-dependent protein ki...

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Detalles Bibliográficos
Autores principales: Lai, Ruosha, Fang, Qiaojun, Wu, Fan, Pan, Song, Haque, Khujista, Sha, Su-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359991/
https://www.ncbi.nlm.nih.gov/pubmed/37484825
http://dx.doi.org/10.3389/fncel.2023.1199656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359991/
https://www.ncbi.nlm.nih.gov/pubmed/37484825
http://dx.doi.org/10.3389/fncel.2023.1199656

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