Cargando…
Rapamycin treatment induces tubular proteinuria: role of megalin-mediated protein reabsorption
Introduction: Rapamycin is an immunosuppressor that acts by inhibiting the serine/threonine kinase mechanistic target of rapamycin complex 1. Therapeutic use of rapamycin is limited by its adverse effects. Proteinuria is an important marker of kidney damage and a risk factor for kidney diseases prog...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359992/ https://www.ncbi.nlm.nih.gov/pubmed/37484026 http://dx.doi.org/10.3389/fphar.2023.1194816 |