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Temporal and spatial staging of lung alveolar regeneration is determined by the grainyhead transcription factor Tfcp2l1

Alveolar epithelial type 2 (AT2) cells harbor the facultative progenitor capacity in the lung alveolus to drive regeneration after lung injury. Using single-cell transcriptomics, software-guided segmentation of tissue damage, and in vivo mouse lineage tracing, we identified the grainyhead transcript...

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Detalles Bibliográficos
Autores principales: Cardenas-Diaz, Fabian L., Liberti, Derek C., Leach, John P., Babu, Apoorva, Barasch, Jonathan, Shen, Tian, Diaz-Miranda, Maria A., Zhou, Su, Ying, Yun, Callaway, Danielle A., Morley, Michael P., Morrisey, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360042/
https://www.ncbi.nlm.nih.gov/pubmed/37119134
http://dx.doi.org/10.1016/j.celrep.2023.112451