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Temporal and spatial staging of lung alveolar regeneration is determined by the grainyhead transcription factor Tfcp2l1
Alveolar epithelial type 2 (AT2) cells harbor the facultative progenitor capacity in the lung alveolus to drive regeneration after lung injury. Using single-cell transcriptomics, software-guided segmentation of tissue damage, and in vivo mouse lineage tracing, we identified the grainyhead transcript...
Autores principales: | Cardenas-Diaz, Fabian L., Liberti, Derek C., Leach, John P., Babu, Apoorva, Barasch, Jonathan, Shen, Tian, Diaz-Miranda, Maria A., Zhou, Su, Ying, Yun, Callaway, Danielle A., Morley, Michael P., Morrisey, Edward E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360042/ https://www.ncbi.nlm.nih.gov/pubmed/37119134 http://dx.doi.org/10.1016/j.celrep.2023.112451 |
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