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Induction of humoral and cell-mediated immunity to the NS1 protein of TBEV with recombinant Influenza virus and MVA affords partial protection against lethal TBEV infection in mice

INTRODUCTION: Tick-borne encephalitis virus (TBEV) is one of the most relevant tick-transmitted neurotropic arboviruses in Europe and Asia and the causative agent of tick-borne encephalitis (TBE). Annually more than 10,000 TBE cases are reported despite having vaccines available. In Europe, the vacc...

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Detalles Bibliográficos
Autores principales: Beicht, Jana, Kubinski, Mareike, Zdora, Isabel, Puff, Christina, Biermann, Jeannine, Gerlach, Thomas, Baumgärtner, Wolfgang, Sutter, Gerd, Osterhaus, Albert D. M. E., Prajeeth, Chittappen Kandiyil, Rimmelzwaan, Guus F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360051/
https://www.ncbi.nlm.nih.gov/pubmed/37483628
http://dx.doi.org/10.3389/fimmu.2023.1177324