Designing New Hybrid Antibiotics: Proline-Rich Antimicrobial Peptides Conjugated to the Aminoglycoside Tobramycin

[Image: see text] Resistance to aminoglycoside antibiotics is a serious problem, typically arising from inactivating enzymes, reduced uptake, or increased efflux in the important pathogens for which they are used as treatment. Conjugating aminoglycosides to proline-rich antimicrobial peptides (PrAMP...

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Detalles Bibliográficos
Autores principales: Gambato, Stefano, Bellotto, Ottavia, Mardirossian, Mario, Di Stasi, Adriana, Gennaro, Renato, Pacor, Sabrina, Caporale, Andrea, Berti, Federico, Scocchi, Marco, Tossi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360068/
https://www.ncbi.nlm.nih.gov/pubmed/37379329
http://dx.doi.org/10.1021/acs.bioconjchem.2c00467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360068/
https://www.ncbi.nlm.nih.gov/pubmed/37379329
http://dx.doi.org/10.1021/acs.bioconjchem.2c00467

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