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Dl-3-n-butylphthalide exerts neuroprotective effects by modulating hypoxia-inducible factor 1-alpha ubiquitination to attenuate oxidative stress-induced apoptosis

Dl-3-n-butylphthalide is used to treat mild and moderate acute ischemic stroke. However, the precise underlying mechanism requires further investigation. In this study, we investigated the molecular mechanism of Dl-3-n-butylphthalide action by various means. We used hydrogen peroxide to induce injur...

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Detalles Bibliográficos
Autores principales: Li, Shuai, Zhao, Jingyuan, Xi, Yan, Ren, Jiaqi, Zhu, Yanna, Lu, Yan, Dong, Deshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360089/
https://www.ncbi.nlm.nih.gov/pubmed/37282472
http://dx.doi.org/10.4103/1673-5374.371366