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The structure of songbird MHC class I reveals antigen binding that is flexible at the N-terminus and static at the C-terminus

Long-distance migratory animals such as birds and bats have evolved to withstand selection imposed by pathogens across the globe, and pathogen richness is known to be particularly high in tropical regions. Immune genes, so-called Major Histocompatibility Complex (MHC) genes, are highly duplicated in...

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Detalles Bibliográficos
Autores principales: Eltschkner, Sandra, Mellinger, Samantha, Buus, Soren, Nielsen, Morten, Paulsson, Kajsa M., Lindkvist-Petersson, Karin, Westerdahl, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360169/
https://www.ncbi.nlm.nih.gov/pubmed/37483599
http://dx.doi.org/10.3389/fimmu.2023.1209059