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Expression of targets of the RNA-binding protein AUF-1 in human airway epithelium indicates its role in cellular senescence and inflammation

INTRODUCTION: The RNA-binding protein AU-rich-element factor-1 (AUF-1) participates to posttranscriptional regulation of genes involved in inflammation and cellular senescence, two pathogenic mechanisms of chronic obstructive pulmonary disease (COPD). Decreased AUF-1 expression was described in bron...

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Detalles Bibliográficos
Autores principales: Salvato, Ilaria, Ricciardi, Luca, Dal Col, Jessica, Nigro, Annunziata, Giurato, Giorgio, Memoli, Domenico, Sellitto, Assunta, Lamparelli, Erwin Pavel, Crescenzi, Maria Assunta, Vitale, Monica, Vatrella, Alessandro, Nucera, Francesco, Brun, Paola, Caicci, Federico, Dama, Paola, Stiff, Thomas, Castellano, Leandro, Idrees, Sobia, Johansen, Matt D., Faiz, Alen, Wark, Peter A., Hansbro, Philip M., Adcock, Ian M., Caramori, Gaetano, Stellato, Cristiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360199/
https://www.ncbi.nlm.nih.gov/pubmed/37483631
http://dx.doi.org/10.3389/fimmu.2023.1192028