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Targeting LSD1 in tumor immunotherapy: rationale, challenges and potential

Lysine-specific demethylase 1 (LSD1) is an enzyme that removes lysine methylation marks from nucleosome histone tails and plays an important role in cancer initiation, progression, metastasis, and recurrence. Recent research shows that LSD1 regulates tumor cells and immune cells through multiple ups...

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Detalles Bibliográficos
Autores principales: Bao, Lei, Zhu, Ping, Mou, Yuan, Song, Yinhong, Qin, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360200/
https://www.ncbi.nlm.nih.gov/pubmed/37483603
http://dx.doi.org/10.3389/fimmu.2023.1214675