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Recombinant protein EBI3 attenuates Clonorchis sinensis-induced liver fibrosis by inhibiting hepatic stellate cell activation in mice

BACKGROUND: Chronic infection with Clonorchis sinensis can cause hepatobiliary fibrosis and even lead to hepatobiliary carcinoma. Epstein-Barr virus-induced gene 3 protein (EBI3) is a subunit of interleukin 35, which can regulate inflammatory response and the occurrence of fibrotic diseases. Previou...

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Detalles Bibliográficos
Autores principales: Zhao, Lei, Li, Jia, Mo, Gang, Cao, Deping, Li, Chun, Huang, Guoyang, Jiang, Liping, Chen, Gen, Yao, Hongbing, Peng, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360228/
https://www.ncbi.nlm.nih.gov/pubmed/37480105
http://dx.doi.org/10.1186/s13071-023-05863-5