Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity

BACKGROUND: The excessive inflammatory responses provoked by SARS-CoV-2 infection are critical factors affecting the severity and mortality of COVID-19. Previous work found that two adjacent co-occurring mutations R203K and G204R (KR) on the nucleocapsid (N) protein correlate with increased disease...

Descripción completa

Detalles Bibliográficos
Autores principales: Shuaib, Muhammad, Adroub, Sabir, Mourier, Tobias, Mfarrej, Sara, Zhang, Huoming, Esau, Luke, Alsomali, Afrah, Alofi, Fadwa S, Ahmad, Adeel Nazir, Shamsan, Abbas, Khogeer, Asim, Hashem, Anwar M., Almontashiri, Naif A. M., Hala, Sharif, Pain, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360309/
https://www.ncbi.nlm.nih.gov/pubmed/37475040
http://dx.doi.org/10.1186/s13073-023-01208-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360309/
https://www.ncbi.nlm.nih.gov/pubmed/37475040
http://dx.doi.org/10.1186/s13073-023-01208-0

Ejemplares similares