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Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity

BACKGROUND: The excessive inflammatory responses provoked by SARS-CoV-2 infection are critical factors affecting the severity and mortality of COVID-19. Previous work found that two adjacent co-occurring mutations R203K and G204R (KR) on the nucleocapsid (N) protein correlate with increased disease...

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Detalles Bibliográficos
Autores principales:	Shuaib, Muhammad, Adroub, Sabir, Mourier, Tobias, Mfarrej, Sara, Zhang, Huoming, Esau, Luke, Alsomali, Afrah, Alofi, Fadwa S, Ahmad, Adeel Nazir, Shamsan, Abbas, Khogeer, Asim, Hashem, Anwar M., Almontashiri, Naif A. M., Hala, Sharif, Pain, Arnab
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360309/ https://www.ncbi.nlm.nih.gov/pubmed/37475040 http://dx.doi.org/10.1186/s13073-023-01208-0

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