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Characterizing the polygenic architecture of complex traits in populations of East Asian and European descent

To investigate the polygenicity of complex traits in populations of East Asian (EAS) and European (EUR) descents, we leveraged genome-wide data from Biobank Japan, UK Biobank, and FinnGen cohorts. Specifically, we analyzed up to 215 outcomes related to 18 health domains, assessing their polygenic ar...

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Detalles Bibliográficos
Autores principales: De Lillo, Antonella, Wendt, Frank R., Pathak, Gita A., Polimanti, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360343/
https://www.ncbi.nlm.nih.gov/pubmed/37475089
http://dx.doi.org/10.1186/s40246-023-00514-3