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Interrogation of human microglial phagocytosis by CRISPR genome editing

BACKGROUND: Microglia are an integral part of central nervous system, but our understanding of microglial biology is limited due to the challenges in obtaining and culturing primary human microglia. HMC3 is an important cell line for studying human microglia because it is readily accessible and stra...

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Detalles Bibliográficos
Autores principales: Chang, Jason Cheng-Yu, Wang, Cheng-You, Lin, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360658/
https://www.ncbi.nlm.nih.gov/pubmed/37483607
http://dx.doi.org/10.3389/fimmu.2023.1169725