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Emodin attenuates high lipid-induced liver metastasis through the AKT and ERK pathways in vitro in breast cancer cells and in a mouse xenograft model

Emodin, a natural anthraquinone derivative, can inhibit lipid synthesis and breast cancer cell proliferation. We previously found that emodin decreased breast cancer liver metastasis via epithelial-to-mesenchymal transition (EMT) inhibition. However, the mechanism through which emodin affects breast...

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Detalles Bibliográficos
Autores principales: Li, Feng, Song, Xiaoyun, Zhou, Xiqiu, Chen, Lili, Zheng, Jinzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361095/
https://www.ncbi.nlm.nih.gov/pubmed/37484373
http://dx.doi.org/10.1016/j.heliyon.2023.e17052