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Cannabinoid and Opioid Receptor Affinity and Modulation of Cancer-Related Signaling Pathways of Machaeriols and Machaeridiols from Machaerium Pers.

Machaeriols and machaeridiols are unique hexahydrodibenzopyran-type aralkyl phytocannabinoids isolated from Machaerium Pers. Earlier studies of machaeriol A (1) and B (2) did not show any affinity for cannabinoid receptor 1 (CB1 or CNR1), although they are structural analogs of psychoactive hexahydr...

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Detalles Bibliográficos
Autores principales: Muhammad, Ilias, Ibrahim, Mohammad A., Kumarihamy, Mallika, Lambert, Janet A., Zhang, Jin, Mohammad, Marwa H., Khan, Shabana I., Pasco, David S., Balachandran, Premalatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361207/
https://www.ncbi.nlm.nih.gov/pubmed/37241903
http://dx.doi.org/10.3390/molecules28104162