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ac4C acetylation regulates mRNA stability and translation efficiency in osteosarcoma

OBJECTIVE: N4-acetylcytidine (ac4C) acetylation can promote target gene expression through improved mRNA stability. To explore the role of ac4C acetylation in osteosarcoma, U2OS and MG63 cell lines were treated with the N-acetyltransferase 10 (NAT10) inhibitor Remodelin. Reverse transcription–polyme...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjie, Gao, Jia, Fan, Lei, Wang, Juan, He, Bin, Wang, Yunhua, Zhang, Xiaotong, Mao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361233/
https://www.ncbi.nlm.nih.gov/pubmed/37484432
http://dx.doi.org/10.1016/j.heliyon.2023.e17103