Regulation of RNG105/caprin1 dynamics by pathogenic cytoplasmic FUS and TDP-43 in neuronal RNA granules modulates synaptic loss

In neurodegenerative diseases, the condensation of FUS and TDP-43 with RNA granules in neurons is linked to pathology, including synaptic disorders. However, the effects of FUS and TDP-43 on RNA granule factors remain unclear. Here, using primary cultured neurons from the mouse cerebral cortex, we s...

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Detalles Bibliográficos
Autores principales: Horio, Tomoyo, Ishikura, Yui, Ohashi, Rie, Shiina, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361247/
https://www.ncbi.nlm.nih.gov/pubmed/37484309
http://dx.doi.org/10.1016/j.heliyon.2023.e17065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361247/
https://www.ncbi.nlm.nih.gov/pubmed/37484309
http://dx.doi.org/10.1016/j.heliyon.2023.e17065

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