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Regulation of RNG105/caprin1 dynamics by pathogenic cytoplasmic FUS and TDP-43 in neuronal RNA granules modulates synaptic loss
In neurodegenerative diseases, the condensation of FUS and TDP-43 with RNA granules in neurons is linked to pathology, including synaptic disorders. However, the effects of FUS and TDP-43 on RNA granule factors remain unclear. Here, using primary cultured neurons from the mouse cerebral cortex, we s...
Autores principales: | Horio, Tomoyo, Ishikura, Yui, Ohashi, Rie, Shiina, Nobuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361247/ https://www.ncbi.nlm.nih.gov/pubmed/37484309 http://dx.doi.org/10.1016/j.heliyon.2023.e17065 |
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