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Fecal Microbiota Transplantation Alleviated Paclitaxel-Induced Peripheral Neuropathy by Interfering with Astrocytes and TLR4/p38MAPK Pathway in Rats

PURPOSE: Paclitaxel-induced peripheral neuropathy (PIPN) constitutes a refractory and progressive adverse consequence of paclitaxel treatment, causing pain and sensory anomalies in cancer survivors. Although the gut-brain axis is involved in multiple disorders including cancer, its impact on periphe...

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Detalles Bibliográficos
Autores principales: Shi, Haibin, Chen, Minmin, Zheng, Caihong, Yinglin, Bian, Zhu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361291/
https://www.ncbi.nlm.nih.gov/pubmed/37483406
http://dx.doi.org/10.2147/JPR.S415642