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Optimization of drug scheduling for cancer chemotherapy with considering reducing cumulative drug toxicity
An improved optimal drug scheduling model with considering two control drugs is proposed and the Gauss pseudospectral-based optimization method is studied to decrease the tumor size and drug toxicity in this work. Firstly, the Dexrazoxane drug, which has significant clinical effect to reduce the tox...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361382/ https://www.ncbi.nlm.nih.gov/pubmed/37484317 http://dx.doi.org/10.1016/j.heliyon.2023.e17297 |