Cargando…

Optimization of drug scheduling for cancer chemotherapy with considering reducing cumulative drug toxicity

An improved optimal drug scheduling model with considering two control drugs is proposed and the Gauss pseudospectral-based optimization method is studied to decrease the tumor size and drug toxicity in this work. Firstly, the Dexrazoxane drug, which has significant clinical effect to reduce the tox...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Ping, Xiao, Qi, Zhai, Shidong, Qu, Hongchun, Guo, Fei, Deng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361382/
https://www.ncbi.nlm.nih.gov/pubmed/37484317
http://dx.doi.org/10.1016/j.heliyon.2023.e17297