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Optimization of drug scheduling for cancer chemotherapy with considering reducing cumulative drug toxicity
An improved optimal drug scheduling model with considering two control drugs is proposed and the Gauss pseudospectral-based optimization method is studied to decrease the tumor size and drug toxicity in this work. Firstly, the Dexrazoxane drug, which has significant clinical effect to reduce the tox...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361382/ https://www.ncbi.nlm.nih.gov/pubmed/37484317 http://dx.doi.org/10.1016/j.heliyon.2023.e17297 |