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Immunologic Characterization and T cell Receptor Repertoires of Expanded Tumor-infiltrating Lymphocytes in Patients with Renal Cell Carcinoma

The successful use of expanded tumor-infiltrating lymphocytes (TIL) in adoptive TIL therapies has been reported, but the effects of the TIL expansion, immunophenotype, function, and T cell receptor (TCR) repertoire of the infused products relative to the tumor microenvironment (TME) are not well und...

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Detalles Bibliográficos
Autores principales: Lee, Moon Hee, Theodoropoulos, Jason, Huuhtanen, Jani, Bhattacharya, Dipabarna, Järvinen, Petrus, Tornberg, Sara, Nísen, Harry, Mirtti, Tuomas, Uski, Ilona, Kumari, Anita, Peltonen, Karita, Draghi, Arianna, Donia, Marco, Kreutzman, Anna, Mustjoki, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361538/
https://www.ncbi.nlm.nih.gov/pubmed/37484198
http://dx.doi.org/10.1158/2767-9764.CRC-22-0514