Glutaredoxin‐1 promotes lymphangioleiomyomatosis progression through inhibiting Bim‐mediated apoptosis via COX2/PGE2/ERK pathway

BACKGROUND: Lymphangioleiomyomatosis (LAM) is a female‐predominant interstitial lung disease, characterized by progressive cyst formation and respiratory failure. Clinical treatment with the mTORC1 inhibitor rapamycin could relieve partially the respiratory symptoms, but not curative. It is urgent t...

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Detalles Bibliográficos
Autores principales: Feng, Ya, Li, Tianjiao, Li, Yin, Lin, Zhoujun, Han, Xiao, Pei, Xiaolin, Zhang, Yupeng, Li, Fei, Yang, Juan, Shao, Di, Li, Chenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361546/
https://www.ncbi.nlm.nih.gov/pubmed/37478294
http://dx.doi.org/10.1002/ctm2.1333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361546/
https://www.ncbi.nlm.nih.gov/pubmed/37478294
http://dx.doi.org/10.1002/ctm2.1333

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