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Primary oxidative phosphorylation defects lead to perturbations in the human B cell repertoire

INTRODUCTION: The majority of studies on oxidative phosphorylation in immune cells have been performed in mouse models, necessitating human translation. To understand the impact of oxidative phosphorylation (OXPHOS) deficiency on human immunity, we studied children with primary mitochondrial disease...

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Detalles Bibliográficos
Autores principales: Gordon-Lipkin, Eliza M., Banerjee, Payal, Franco, Jose Luis Marin, Tarasenko, Tatiana, Kruk, Shannon, Thompson, Elizabeth, Gildea, Derek E., Zhang, Suiyuan, Wolfsberg, Tyra G., Flegel, Willy A., McGuire, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361569/
https://www.ncbi.nlm.nih.gov/pubmed/37483601
http://dx.doi.org/10.3389/fimmu.2023.1142634