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Caspase-mediated LPS sensing and pyroptosis signaling in Hydra

Inflammatory caspases sensing lipopolysaccharide (LPS) to drive gasdermin (GSDM)–mediated pyroptosis is an important immune response mechanism for anti-infection defense in mammals. In this work, we resolved an LPS-induced and GSDM-gated pyroptosis signaling cascade in Cnidarians. Initially, we iden...

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Detalles Bibliográficos
Autores principales: Chen, Shouwen, Li, Shuxin, Chen, Hao, Gong, Yuxin, Yang, Dahai, Zhang, Yuanxing, Liu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361584/
https://www.ncbi.nlm.nih.gov/pubmed/37478191
http://dx.doi.org/10.1126/sciadv.adh4054