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The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production
Vascular cognitive impairment (VCI) refers to cognitive alterations caused by vascular disease, which is associated with various types of dementia. Because chronic cerebral hypoperfusion (CCH) induces VCI, we used bilateral common carotid artery stenosis (BCAS) mice as a CCH-induced VCI model. Trans...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361588/ https://www.ncbi.nlm.nih.gov/pubmed/37478173 http://dx.doi.org/10.1126/sciadv.adh0102 |