The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production

Vascular cognitive impairment (VCI) refers to cognitive alterations caused by vascular disease, which is associated with various types of dementia. Because chronic cerebral hypoperfusion (CCH) induces VCI, we used bilateral common carotid artery stenosis (BCAS) mice as a CCH-induced VCI model. Trans...

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Detalles Bibliográficos
Autores principales: Kakae, Masashi, Nakajima, Hiroki, Tobori, Shota, Kawashita, Ayaka, Miyanohara, Jun, Morishima, Misa, Nagayasu, Kazuki, Nakagawa, Takayuki, Shigetomi, Eiji, Koizumi, Schuichi, Mori, Yasuo, Kaneko, Shuji, Shirakawa, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361588/
https://www.ncbi.nlm.nih.gov/pubmed/37478173
http://dx.doi.org/10.1126/sciadv.adh0102

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