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Refinement of AlphaFold2 models against experimental and hybrid cryo-EM density maps

Recent breakthroughs in deep learning-based protein structure prediction show that it is possible to obtain highly accurate models for a wide range of difficult protein targets for which only the amino acid sequence is known. The availability of accurately predicted models from sequences can potenti...

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Detalles Bibliográficos
Autores principales: Alshammari, Maytha, Wriggers, Willy, Sun, Jiangwen, He, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361706/
https://www.ncbi.nlm.nih.gov/pubmed/37485023
http://dx.doi.org/10.1017/qrd.2022.13