Structure of the HIV immature lattice allows for essential lattice remodeling within budded virions

For HIV virions to become infectious, the immature lattice of Gag polyproteins attached to the virion membrane must be cleaved. Cleavage cannot initiate without the protease formed by the homo-dimerization of domains linked to Gag. However, only 5% of the Gag polyproteins, termed Gag-Pol, carry this...

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Detalles Bibliográficos
Autores principales: Guo, Sikao, Saha, Ipsita, Saffarian, Saveez, Johnson, Margaret E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361719/
https://www.ncbi.nlm.nih.gov/pubmed/37435945
http://dx.doi.org/10.7554/eLife.84881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361719/
https://www.ncbi.nlm.nih.gov/pubmed/37435945
http://dx.doi.org/10.7554/eLife.84881

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