Plasmablasts in previously immunologically naïve COVID-19 patients express markers indicating mucosal homing and secrete antibodies cross-reacting with SARS-CoV-2 variants and other beta-coronaviruses

Antigen-specific class-switched antibodies are detected at the same time or even before IgM in serum of non-vaccinated individuals infected with SARS-CoV-2. These derive from the first wave of plasmablasts formed. Hence, the phenotype and specificity of plasmablasts can reveal information about earl...

Descripción completa

Detalles Bibliográficos
Autores principales: Lundgren, Anna, Leach, Susannah, Axelsson, Hannes, Isakson, Pauline, Nyström, Kristina, Scharf, Lydia, Andersson, Bengt A, Miron, Nicolae, Marklund, Emelie, Andersson, Lars-Magnus, Gisslén, Magnus, Angeletti, Davide, Bemark, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Review Series: Human B Cells (Series Editors: Jo Spencer, Mats Bemark, Thomas J. Tull)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361743/
https://www.ncbi.nlm.nih.gov/pubmed/37071584
http://dx.doi.org/10.1093/cei/uxad044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361743/
https://www.ncbi.nlm.nih.gov/pubmed/37071584
http://dx.doi.org/10.1093/cei/uxad044

Ejemplares similares