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Plasmablasts in previously immunologically naïve COVID-19 patients express markers indicating mucosal homing and secrete antibodies cross-reacting with SARS-CoV-2 variants and other beta-coronaviruses
Antigen-specific class-switched antibodies are detected at the same time or even before IgM in serum of non-vaccinated individuals infected with SARS-CoV-2. These derive from the first wave of plasmablasts formed. Hence, the phenotype and specificity of plasmablasts can reveal information about earl...
Autores principales: | Lundgren, Anna, Leach, Susannah, Axelsson, Hannes, Isakson, Pauline, Nyström, Kristina, Scharf, Lydia, Andersson, Bengt A, Miron, Nicolae, Marklund, Emelie, Andersson, Lars-Magnus, Gisslén, Magnus, Angeletti, Davide, Bemark, Mats |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361743/ https://www.ncbi.nlm.nih.gov/pubmed/37071584 http://dx.doi.org/10.1093/cei/uxad044 |
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