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Arc protein, a remnant of ancient retrovirus, forms virus-like particles, which are abundantly generated by neurons during epileptic seizures, and affects epileptic susceptibility in rodent models

A product of the immediate early gene Arc (Activity-regulated cytoskeleton-associated protein or Arc protein) of retroviral ancestry resides in the genome of all tetrapods for millions of years and is expressed endogenously in neurons. It is a well-known protein, very important for synaptic plastici...

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Detalles Bibliográficos
Autores principales: Sibarov, Dmitry A., Tsytsarev, Vassiliy, Volnova, Anna, Vaganova, Anastasia N., Alves, Janaina, Rojas, Legier, Sanabria, Priscila, Ignashchenkova, Alla, Savage, Elton D., Inyushin, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361770/
https://www.ncbi.nlm.nih.gov/pubmed/37483450
http://dx.doi.org/10.3389/fneur.2023.1201104