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Arc protein, a remnant of ancient retrovirus, forms virus-like particles, which are abundantly generated by neurons during epileptic seizures, and affects epileptic susceptibility in rodent models
A product of the immediate early gene Arc (Activity-regulated cytoskeleton-associated protein or Arc protein) of retroviral ancestry resides in the genome of all tetrapods for millions of years and is expressed endogenously in neurons. It is a well-known protein, very important for synaptic plastici...
Autores principales: | Sibarov, Dmitry A., Tsytsarev, Vassiliy, Volnova, Anna, Vaganova, Anastasia N., Alves, Janaina, Rojas, Legier, Sanabria, Priscila, Ignashchenkova, Alla, Savage, Elton D., Inyushin, Mikhail |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361770/ https://www.ncbi.nlm.nih.gov/pubmed/37483450 http://dx.doi.org/10.3389/fneur.2023.1201104 |
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