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Nonequilibrium thermodynamics and mitochondrial protein content predict insulin sensitivity and fuel selection during exercise in human skeletal muscle

Introduction: Many investigators have attempted to define the molecular nature of changes responsible for insulin resistance in muscle, but a molecular approach may not consider the overall physiological context of muscle. Because the energetic state of ATP (ΔG(ATP)) could affect the rate of insulin...

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Detalles Bibliográficos
Autores principales: Zapata Bustos, Rocio, Coletta, Dawn K., Galons, Jean-Philippe, Davidson, Lisa B., Langlais, Paul R., Funk, Janet L., Willis, Wayne T., Mandarino, Lawrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361819/
https://www.ncbi.nlm.nih.gov/pubmed/37485059
http://dx.doi.org/10.3389/fphys.2023.1208186