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Nonequilibrium thermodynamics and mitochondrial protein content predict insulin sensitivity and fuel selection during exercise in human skeletal muscle
Introduction: Many investigators have attempted to define the molecular nature of changes responsible for insulin resistance in muscle, but a molecular approach may not consider the overall physiological context of muscle. Because the energetic state of ATP (ΔG(ATP)) could affect the rate of insulin...
Autores principales: | Zapata Bustos, Rocio, Coletta, Dawn K., Galons, Jean-Philippe, Davidson, Lisa B., Langlais, Paul R., Funk, Janet L., Willis, Wayne T., Mandarino, Lawrence J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361819/ https://www.ncbi.nlm.nih.gov/pubmed/37485059 http://dx.doi.org/10.3389/fphys.2023.1208186 |
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