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Muscle fiber necroptosis in pathophysiology of idiopathic inflammatory myopathies and its potential as target of novel treatment strategy

Idiopathic inflammatory myopathies (IIMs), which are a group of chronic and diverse inflammatory diseases, are primarily characterized by weakness in the proximal muscles that progressively leads to persistent disability. Current treatments of IIMs depend on nonspecific immunosuppressive agents (inc...

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Detalles Bibliográficos
Autores principales: Kamiya, Mari, Kimura, Naoki, Umezawa, Natsuka, Hasegawa, Hisanori, Yasuda, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361824/
https://www.ncbi.nlm.nih.gov/pubmed/37483632
http://dx.doi.org/10.3389/fimmu.2023.1191815