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Discordance of PIK3CA mutational status between primary and metastatic breast cancer: a systematic review and meta-analysis

INTRODUCTION: In light of the clinically meaningful results of the PI3K inhibitors in PIK3CA-mutated metastatic breast cancer (BC) patients, the reliable identification of PIK3CA mutations is of outmost importance. However, lack of evidence on the optimal site and timing of assessment, presence of t...

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Detalles Bibliográficos
Autores principales: Rosin, Justus, Svegrup, Ella, Valachis, Antonios, Zerdes, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361863/
https://www.ncbi.nlm.nih.gov/pubmed/37392328
http://dx.doi.org/10.1007/s10549-023-07010-1