Cytotoxicity of CD19-CAR-NK92 cells is primarily mediated via perforin/granzyme pathway

Chimeric antigen receptors (CARs) have improved cancer immunotherapy in recent years. Immune cells, such as Natural killer cells (NK-cells) or T cells, are used as effector cells in CAR-therapy. NK92-cells, a cell line with known cytotoxic activity, are of particular interest in CAR-therapy since cu...

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Detalles Bibliográficos
Autores principales: Althaus, Jonas, Nilius-Eliliwi, Verena, Maghnouj, Abdelouahid, Döring, Sascha, Schroers, Roland, Hudecek, Michael, Hahn, Stephan A., Mika, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361870/
https://www.ncbi.nlm.nih.gov/pubmed/37052701
http://dx.doi.org/10.1007/s00262-023-03443-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361870/
https://www.ncbi.nlm.nih.gov/pubmed/37052701
http://dx.doi.org/10.1007/s00262-023-03443-1

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