Enhanced HPV16 E6/E7(+) tumor eradication via induction of tumor-specific T cells by therapeutic vaccination with virosomes presenting synthetic long peptides

Therapeutic cancer vaccines trigger CD4 + and CD8 + T cell responses capable of established tumor eradication. Current platforms include DNA, mRNA and synthetic long peptide (SLP) vaccines, all aiming at robust T cell responses. SLPs linked to the Amplivant® adjuvant (Amplivant-SLP) have shown effec...

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Detalles Bibliográficos
Autores principales: Stegmann, Toon, Wiekmeijer, Anna-Sophia, Kwappenberg, Kitty, van Duikeren, Suzanne, Bhoelan, Farien, Bemelman, Denzel, Beenakker, Thomas J. M., Krebber, Willem-Jan, Arens, Ramon, Melief, Cornelis J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361876/
https://www.ncbi.nlm.nih.gov/pubmed/37222770
http://dx.doi.org/10.1007/s00262-023-03462-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361876/
https://www.ncbi.nlm.nih.gov/pubmed/37222770
http://dx.doi.org/10.1007/s00262-023-03462-y

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